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Plant Extracts Display Synergism with Different Classes of Antibiotics Anais da ABC (AABC)
SILVA,DANIELLE M.; COSTA,PRISCILLA A. DA; RIBON,ANDRÉA O.B.; PURGATO,GISLAINE A.; GASPAR,DIAZ-MUÑOZ; DIAZ,MARISA A.N..
Abstract: One manner in which plant-derived compounds exert their antibiotic potential is the synergism, a positive interaction between two compounds. Studies indicate that the use of plant extracts combined with antimicrobials may promote a significant reduction of the minimum inhibitory concentrations of antibiotics for bacterial strains. This study aimed to evaluate the activity of plant extracts and antibiotics as well as their combination on Staphylococcus aureus. The activity of 15 plant extracts was evaluated using diffusion assay. The minimum inhibitory concentrations (MICs) and the interactions between the extracts and antibiotics as well as compound emodin were evaluated with the checkerboard method. The active extracts were a hexane extract of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotics; Bovine mastitis; Plant extract; Staphylococcus aureus.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300802
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